Drosophila Atrophin Homolog Functions as a Transcriptional Corepressor in Multiple Developmental Processes
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چکیده
منابع مشابه
Drosophila Atrophin Homolog Functions as a Transcriptional Corepressor in Multiple Developmental Processes
Dentatorubral-pallidoluysian atrophy is a progressive neurodegenerative disease caused by the expansion of a polyglutamine repeats within the Atrophin-1 protein. The in vivo function of Atrophin-1 is unknown. We have characterized a Drosophila gene encoding an Atrophin family protein. Analysis of mutant phenotypes indicates that Drosophila Atrophin is required in diverse developmental processes...
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ژورنال
عنوان ژورنال: Cell
سال: 2002
ISSN: 0092-8674
DOI: 10.1016/s0092-8674(01)00630-4